QuellTX Logo

Scientist – Process Development

Location: White City, London

ABOUT US

At Quell we seek to deliver truly innovative, life-changing therapies for our patients. Our vision as a company is to build a major global biopharmaceutical company bringing transformational and valued therapies for a range of autoimmune and inflammatory diseases, as well as preventing rejection in organ transplantation, based on modular engineered Tregs.

 

OUR COMPANY

Quell was founded in March 2019 in partnership with six prominent immunological experts from King’s College London, University College London, and Hannover Medical School, and is led by Iain McGill, a leading pharmaceutical executive with extensive relevant experience, having spent most of his 25 years in the industry in immunology, including the areas of solid organ and cell transplantation. The Company was founded with initial series A financing, led by Syncona Ltd who committed £59M with a further £2M contributed by UCL Technology Fund.

 

THE ROLE

Scientist – Process Development

We are looking to recruit a Scientist to expand our Process Development team. The successful candidate will be involved in the development of manufacturing processes for our next-generation cell therapies. This individual will work closely with Scientists and Research Associates within the team to design and conduct experiments, presenting findings at meetings. They will also collaborate with other teams in R&D and CMC to progress the development of the Company’s portfolio.

 

This position offers an excellent opportunity for a talented and motivated Scientist to contribute to a key part of our work. Quell offers an exciting and highly dynamic environment focused on developing cutting-edge Treg therapies.

 

MAIN RESPONSIBILITIES

  • Provide technical expertise, and practical capacity to the Process Development team
  • Contribute to improvement of existing process design, regarding efficiency and quality
  • Assist in designing, conducting, optimizing and evaluating new processes for translation into a GMP environment
  • Assist in technology transfer to the GMP manufacturing team
  • Manage process development related activities across multiple projects and providing technical leadership for completing projects with minimal supervision.
  • Maintain highly organised and detailed documentation of experimental procedures and establish relevant SOPs.
  • Analyse data in a timely manner and present findings at team/departmental meetings.
  • Stay up-to-date with literature and new technologies within the cell therapy field.
  • Collaborate and coordinate work with other teams to meet deadlines and goals.

 

ESSENTIAL SKILLS AND EXPERIENCE

  • Minimum BSc degree in a relevant study field and relevant industry experience
  • Solid understanding of immunology and cell therapy.
  • Demonstrable expertise in cell-based processing including cell isolation, culture and cryopreservation
  • Demonstrable expertise in cell-based techniques including flow cytometry, ELISA, qPCR
  • Experience with closed-system cell processing systems and bioreactors
  • Ability to perform experiments independently
  • Resourcefulness in overcoming challenges and possess the ability to thrive in a fast-paced environment.
  • Excellent time and project management skills.
  • Proven commitment to high quality work and maintenance of high standards.

 

DESIRABLE SKILLS AND EXPERIENCE

  • Practical experience implementing design of experiments to develop processes
  • Understanding of risk-based approaches to process development including Quality-by-design (QbD) principles
  • Practical experience implementing design of experiments (DoE) to develop processes.
  • Directly relevant biotechnology or pharmaceutical industry experience.
  • Previous experience of using electronic lab notebooks

 

PERSONAL QUALITIES

  • Ability to work collaboratively within a team, supporting one another and held accountable for project deliverables.
  • Personal drive and goal orientation.
  • Detail-orientated and accurate.
  • Professional and personable communication skills.
  • Driven to solve problems pragmatically.
  • Demonstrates strong organisational and prioritisation skills to manage a diverse workload.
  • Good working attitude, reliability, and flexibility.
  • Desire to work with integrity and act as an ambassador for Quell and the wider business.

 

BENEFITS

  • Holidays: 25 days per year.
  • Life Assurance: 4 x base salary.
  • Group Personal Pension: Auto enrolled at 4% employer contribution, 4% employee contribution.
  • Private Medical Insurance for your whole family.
  • Annual Bonus.

 

PERKS

  • Fantastic collaborative environment at Translation & Innovation Hub
  • £Million Investment including brand new lab equipment, innovative methods, and exposure to cutting edge technology.
  • Flexible working.
  • Fast paced and progressive company looking for future leaders and innovators.

Application Form






    Please confirm you are eligible to work in the UK.

    Upload CV