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Senior Scientist – Translational

Location: White City, London


At Quell we seek to deliver truly innovative, life-changing therapies for our patients. Our vision as a company is to build a major global biopharmaceutical company bringing transformational and valued therapies for a range of autoimmune and inflammatory diseases, as well as preventing rejection in organ transplantation, based on modular engineered Tregs.



Quell was founded in March 2019 in partnership with six prominent immunological experts from King’s College London, University College London, and Hannover Medical School, and is led by Iain McGill, a leading pharmaceutical executive with extensive relevant experience, having spent most of his 25 years in the industry in immunology, including the areas of solid organ and cell transplantation. The Company was founded with initial series A financing, led by Syncona Ltd who committed £34M with a further £1M contributed by UCL Technology Fund.


Senior Scientist – Translational

Quell therapeutics is seeking to expand our Translational and product knowledge team by recruiting a Senior Scientist with experience running an immunomonitoring programme for a clinical trial. Expertise in Treg Immunology and CAR T technology is a plus. The successful candidate will have a passion for driving high-impact projects focused on the development of novel immune-therapeutics. The successful candidate will effectively and routinely collaborate with colleagues on different projects and regularly present scientific results to multidisciplinary teams and leadership at Quell therapeutics.


  • Manage, mentor, and train a group of Research Associates and Scientists
  • Manage and coordinate all the work involved in the immunomonitoring program of the clinical trial
  • Manage and coordinate all the work involved in preparing and qualifying the immunomonitoring assays
  • Data supervision, collection and analysis
  • Generate presentations and communicate effectively the immunomonitoring data
  • Manage the relations with CRO’s
  • Manage and implement various projects collaborating with other departments
  • Manage and support external collaborations as a subject matter expert in immunology
  • Contribute to the external scientific visibility of the company through collaboration with industry partners


  • Previous people supervisory or management experience
  • Extensive experience on immunomonitoring tools in a clinical trial setting
  • Extensive experience working with clinical samples
  • Extensive experience in T-Cell/ T-Reg and immunoassays optimisation
  • Characterization of immune cell populations using flow cytometry and molecular biology tools
  • Work independently or collaboratively as part of a team; manage multiple projects simultaneously
  • Demonstrate the ability to critically analyse and present data
  • Contribute to a culture that embraces scientific excellence, integrity, urgency, patient centricity, and continuous improvement
  • Post doc/ Post PhD industry experience


  • PhD in Immunology or related subject
  • At least 5years direct industry experience in Treg-cell biology or equivalent experience
  • Experience in immune monitoring of clinical trials and biomarker discovery
  • Deep knowledge of principles of Treg immunology and broad knowledge of current concepts in CAR technology
  • Management experience
  • Expertise in the culture of primary human cells and methods such as multi-colour flow cytometry, ELISA, ELISpot. TCR and RNA single cell sequencing as a plus


  • Ability to work collaboratively within a team, supporting one another and held accountable for project deliverables
  • Motivation and determination to meet specified objectives
  • Flexibility and ability to provide help and support to colleagues as and when required
  • Professional and personable communication skills within a close-knit team and senior stakeholders of the business
  • Driven to solve problems pragmatically in an innovate way
  • Take pride and respect in leading a team effectively and efficiently
  • Desire to work with integrity and act as an ambassador for Quell and the wider business
  • Strong work ethic and a team orientation


  • Holidays: 25 days per year
  • Life Assurance: 4 x base salary
  • Group Personal Pension: Auto enrolled at 4% employer contribution, 4% employee contribution
  • Private Medical Insurance for your whole family
  • Annual Bonus


  • Fantastic collaborative environment at Translation & Innovation Hub
  • Click here for Virtual Tour
  • £36 Million Investment including brand new lab equipment, innovative methods, and exposure to cutting edge technology
  • Flexible working
  • Fast paced and progressive company looking for future leaders and innovators

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