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Engineering Multi-modular Tregs with CARs, a Foxp3 Phenotype Lock and Synthetic Cytokine Receptors enhances their therapeutic potential for a broad range of immune conditions

Sim Tung, Bethany McCloskey, Somayya Manzoor, Mahnoor Irfan, Julieta Karegli, Joanne Anstee, Marco Romano, Yasaman Shahrabi, Amy Billman, Evanthia Nikolopoulou, Jenny McGovern, Daniela Penston, Nathalie Belmonte, Marc Martinez-Llordella, Tracey Lodie

The Future of Regulatory T Cell Therapy: Promises and Challenges of Implementing CAR Technology

Yasmin R. Mohseni, Sim L. Tung1, Caroline Dudreuilh, Robert I. Lechler, Gilbert O. Fruhwirth and Giovanna Lombardi

Applicability, Safety And Biological Activity Of Regulatory T Cell Therapy In Liver Transplantation

Sanchez-Fueyo et al. - 2019

Cell Therapy in Organ Transplantation: Our Experience on the Clinical Translation of Regulatory T Cells

Safinia et al. - 2019

Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection

Boardman et al. - 2017

Regulatory T‐cell therapy in liver transplantation

Whitehouse et al. - 2017

Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC‐Specific Chimeric Antigen Receptor

Noyan et al. - 2016

Prospective multicenter clinical trial of immunosuppressive drug withdrawal in stable adult liver transplant recipients

Benitez et al - 2013

Adoptive therapy with redirected primary regulatory T cells results in antigen-specific suppression of arthritis

Wright et al. 2009