Quell Therapeutics

Uncover our world leading platform

Uncover our world leading platform

On the pursuit to develop the most stable and potent targeted Treg cell therapies

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Tregs

The masters of immune tolerance

Regulatory T cells (Tregs) are the body's masterful immune modulators, expertly orchestrating the immune system to strike the perfect balance between immune defence and self tolerance

Convert

Convert pathogenic cells to good cells

Tregs convert

Description

Tregs drive the conversion of conventional and pathogenic T cells into induced Tregs via the generation of a localized tolerogenic milieu, amplifying the durability of the immune suppressive environment.

Mechanism

Immunosuppressive cytokine pathways (TGFbeta, IL-10, IL-35)

Modulation of antigen-presenting cells (Costim-stripping, CTLA-4, LAG-3, PD-1)

Metabolic disruption (adenosine pathway)

Our Platform

with the optimal cell product at our core and a suite of innovative technologies to ensure continued trailblazing progress

Manufacturing Process

We are a clinical stage company at the forefront of the Treg cell therapy field. With deep GMP experience and over several hundred scale runs to date, we pride ourselves on the continued delivery of the highest manufacturing standards. Our experience at therapeutic scale has driven significant improvements, making our manufacturing process highly efficient, stable, and effective for delivering transformative cell products to patients.